BreastCancer
Focus on Breast Cancer
dall'ASCO® 2021 Annual Meeting

Poster podcast

ABC

The prognostic performance of PREDICT+ in patients with HER2+ early-stage breast cancer

Autore: Elisa Agostinetto

Institut Jules Bordet and Université Libre de Bruxelles, Belgium; HumanitasClinical and Research Center, IRCCS, Rozzano (MI)

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ABC

eMonarcHER: A phase 3 study of abemaciclib plus standard adjuvant endocrine therapy in patients with HR+/HER2+, node-positive, high-risk early breast cancer

Autore: Sara M. Tolaney

Dana-Farber Cancer Institute, Boston, MA; USA

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PBC

Clinical trial testing superiority of combination plinabulin and pegfilgrastim versus peg alone in breast cancer treated with high-risk febrile neutropenia risk chemotherapy: Final results of the phase 3 protective-2 in chemo-induced neutropenia prevention

Autore: Douglas W. Blayney

Stanford Cancer Center, Stanford University, Stanford, CA; USA

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CE-BC

Cost-effectiveness of the Oncotype DX Breast Recurrence Score test in postmenopausal women with node-positive early breast cancer based on the RxPONDER trial

Autore: Vladislav Berdunov

PHMR Ltd, London, UK

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ABC

ADAPTlate: A randomized, controlled, open-label, phase III trial on adjuvant dynamic marker—Adjusted personalized therapy comparing abemaciclib combined with standard adjuvant endocrine therapy versus standard adjuvant endocrine therapy in (clinical or genomic) high-risk, HR+/HER2- early breast cancer

Autore: Oleg Gluz

West German Study Group and Ev. Hospital Bethesda, Breast Center Niederrhein, Moenchengladbach, and University Hospital Cologne, Germany

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MBC

Updated results of tucatinib versus placebo added to trastuzumab and capecitabine for patients with pretreated HER2+ metastatic breast cancer with and without brain metastases (HER2CLIMB)

Autore: Giuseppe Curigliano

Istituto Europeo di Oncologia, IRCS, Milano, e Università di Milano

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MBC

Real-world cost-effectiveness of pertuzumab with trastuzumab + chemo in patients with metastatic breast cancer: A population-based retrospective cohort study by the Canadian Real-world Evidence for Value in Cancer Drugs (CanREValue) collaboration

Autore: Wei Fang Dai

Temerty Faculty of Medicine, University of Toronto, Canada

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MBC

AMEERA-1: Phase 1/2 study of amcenestrant (SAR439859), an oral selective estrogen receptor degrader, with palbociclib in postmenopausal women with ER+/HER2- metastatic breast cancer

Autore: Sarat Chandarlapaty

Memorial Sloan Kettering Cancer Center, New York, NY; USA

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BC

A phase Ib study of xentuzumab plus abemaciclib and fulvestrant in patients with advanced HR+/HER2-negative breast cancer with visceral or non-visceral disease

Autore: Douglas Yee

Masonic Cancer Center, University of Minnesota, Minneapolis, MN; USA

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MBC

Results from CONTESSA 2: A multinational, multicenter, phase 2 study of tesetaxel plus a reduced dose of capecitabine in patients with hormone receptor + (HR+), HER2- metastatic breast cancer not previously treated with a taxane

Autore: Lee Schwartzberg

West Cancer Center and Research Institute, New York, NY; USA

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MBC

Real-world clinical outcomes on alpelisib in patients with breast cancer and PIK3CA mutations

Autore: Hope Rugo

Div. of Hematology and Oncology, University of California, San Francisco, CA; USA

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MBC

Metastasectomy versus radiation of secondary sites in stage IV breast cancer

Autore: Nadeem Bilani

Cleveland Clinic Florida, Fort Lauderdale, FL; USA

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MBC

SERENA-4: A phase 3 comparison of AZD9833 (camizestrant) plus palbociclib, versus anastrozole plus palbociclib, for patients with ER-positive, HER2-negative advanced breast cancer who have not previously received systemic treatment for advanced disease

Autore: Seock-Ah Im

Seoul National University Cancer Hospital, Seoul, Rep. of Korea

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MBC

Trial in progress: A phase 3, randomized, double-blind trial of trilaciclib versus placebo in patients receiving first- or second-line gemcitabine and carboplatin for locally advanced unresectable or metastatic triple-negative breast cancer (PRESERVE 2)

Autore: Shom Goel

Peter MacCallum Cancer Centre, Melbourne, VIC; Australia

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MBC

Decreased enrollment of patients with advanced lobular breast cancer compared to ductal breast cancer in interventional clinical trials

Autore: Mary Kathryn Abel

University of California, School of Medicine and Dept. of Surgery, San Francisco, CA; USA

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